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JoVE Journal Developmental Biology
Evaluering af spindelsamlingens kontrolpunktintegritet i museoocytter
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Evaluering af spindelsamlingens kontrolpunktintegritet i museoocytter

Article DOI: 10.3791/64459-v • 10:09 min • September 13th, 2022
September 13th, 2022 •
1,2,3, 1,2, 1,2
1Department of Genetics, Rutgers, The State University of New Jersey, 2Human Genetics Institute of New Jersey, 3Department of Theriogenology, Faculty of Veterinary Medicine, Mansoura University

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Fejl i kromosomadskillelse er et almindeligt træk ved oocytter. Derfor giver undersøgelse af spindelsamlingskontrolpunktet vigtige spor om de mekanismer, der er nødvendige for at producere sunde æg. Denne protokol beskriver tre komplementære assays til evaluering af spindelsamlingens kontrolpunktintegritet i museoocytter.

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Udviklingsbiologi udgave 187
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