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Method Article

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

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DOI:

10.3791/57323

March 26th, 2018

In This Article

Summary

The goal of this protocol is to describe in detail the technique of minimally invasive aortic valve replacement through a right anterior mini-thoracotomy and central aortic cannulation. This technique can potentially enhance patients' comfort and, by reducing post-operative morbidity, promote lowering the length of stay and global costs.

Abstract

Aortic valve stenosis has become the most prevalent valvular heart disease in developed countries, and is due to the aging of these populations. The incidence of the pathology increases with growing age after 65 years. Conventional surgical aortic valve replacement through median sternotomy has been the gold standard of patient care for symptomatic aortic valve stenosis. However, as the risk profile of patients worsens, other therapeutic strategies have been introduced in an attempt to maintain the excellent results obtained by the established surgical treatment. One of these approaches is represented by transcatheter aortic valve implantation. Although the outcomes of high-risk patients undergoing treatment for symptomatic aortic valve stenosis have improved with transcatheter aortic valve replacement, many patients with this condition remain candidates for surgical aortic valve replacement. In order to reduce the surgical trauma in patients who are candidates for surgical aortic valve replacement, minimally invasive approaches have garnered interest during the past decade. Since the introduction of right anterior thoracotomy for aortic valve replacement in 1993, right anterior mini-thoracotomy and upper hemi-sternotomy have become the predominant incisional approaches among cardiac surgeons performing minimal access aortic valve replacement. Beside the location of the incision, the arterial cannulation site represents the second major landmark of minimal access techniques for aortic valve replacement. The two most frequently used arterial cannulation sites include central aortic and peripheral femoral approaches. With the purpose of reducing surgical trauma in these patients, we have opted for a right anterior mini-thoracotomy approach with a central aortic cannulation site. This protocol describes in detail a technique for minimally invasive aortic valve replacement and provides recommendations for patient selection criteria, including cardiac computer tomography measurements. The indications and limitations of this technique, as well as its alternatives, are discussed.

Introduction

Among heart valve lesions diagnosed as hemodynamically relevant and clinically receiving particular attention, aortic valve stenosis is the most common valvular pathology in the United States and developed countries1,2. In the Cardiovascular Health Study, 2% of patients had frank aortic stenosis, with a clear increase in prevalence with growing age: 1.3% in patients aged 65-75 years, 2.4% in those aged 75-85 years, and 4% in patients older than 85 years1. For symptomatic patients presenting with severe aortic valve stenosis, aortic valve replacement is a Class I recommendation in the gu....

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Protocol

The protocol follows our institutional guidelines of the human research ethics committee.

1. Patient Selection (Table 1)

  1. Identify patients necessitating isolated aortic valve replacement14.
  2. Select among these patients a subgroup without major chest deformities (Kypho-scoliosis), previous history of irradiation or surgery of the right hemi-thorax, need for emergency operation, and operation for active endocarditis.
  3. Perform a chest computed tomography (CT) scan to exclude patients with ascending aortic aneurysm ≥4.5 cm.
  4. Make the final decision according to the measurement....

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Results

Statistical analysis is done for continuous variables (presented as means ± SD) in Table 2, Table 3, and Table 4 using the non-parametric Mann Whitney test. Categorical variables are presented as percentages in Table 2, Table 3, and Table 4, and are compared by the Chi-square test. The statistical analyses are performed using commercially available software, with a statistical significanc.......

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Discussion

In this protocol, we describe in detail the technique of right anterior mini-thoracotomy for isolated aortic valve replacement, and highlight the patient selection criteria for this procedure. As for any other therapeutic intervention, proper patient selection is the key to successful accomplishment of the procedure. The optimal CT measurements for consideration of patients for this technique are precisely described in this protocol, and are based on experience and consider the extensive work of Dr. Glauber and coworkers.......

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Disclosures

The authors have nothing to disclose.

Acknowledgements

This work was supported by a grant (N° 32119) of the Swiss Cardiovascular Foundation to RT.

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Materials

List of materials used in this article
NameCompanyCatalog NumberComments
Heart surgery infrastructure:
Heart Lung MachineStockertSIII
EOPA 24Fr. arterial cannulaMedtronic77624
FemFlex arterial cannulaEdwardsFEMII20A
Quickdraw 25Fr. femoral venous cannulaEdwardsQD25
Biomedicus 25Fr. Nextgen venous cannulaMedtronic96670-125
LV vent catheter 17Fr.EdwardsE061
Antegrade 9Fr. cardioplegia cannulaEdwardsAR012V
Coronary artery ostial cannula 90°Medtronic30155
Coronary artery ostial cannula 45°Medtronic30255
Soft tissue retractor
STAR soft tissue atraumatic retractorEstechEC400220
Soft tissue retractorEdwardsTRM
ElectrocauteryCovidienForce FXTM
Sutures:
Polypropylene 4/0Ethicon8871H
Polypropylene 5/0Ethicon8870H
Braided polyesther 2/0 ligature with polybutylate coating EthiconX305H
Braided polyesther2/0 with pledgets V5EthiconMEH7715N
Braided polyglactin 2/0 sutureEthiconV114H
Braided polyglactin 0 sutureEthiconW9996
Drugs:
MidazolamRoche PharmaN05CD08
RocuroniumMSD Merck Sharp & Dohme M03AC09
PropofolFresenius KabiN01AX10
FentanilActavisN01AH01
HeparinBraunB01AB01
ProtaminMEDA PharmaceuticalV03AB14
Custodiol cardioplegia solutionDr. F. Köhler Chemie GmbHB05CX10
Instruments:
Window access retractor SIEstech400-400
SI retractor blade 40W50LEstech400-172
Ceramo atraumatic forceps 2.8x15/350FehlingFE-MRA-3
Ceramo HCR valve forceps 3.0x15/350FehlingFE-MRA-0
Ceramo HCR needle holder 2x10/340FehlingFE-MRB-2
Ceramo TC HCR needle holder curved 3x10/340FehlingFE-MRG-9
Ceramo HCR valve scissors 350FehlingFE-MRA-7
Ceramo HCR curved scissors 350FehlingFE-MRA-6
Cygnet flexible arched aortic clampVitalitecV10143
Intrack insert set double tractionVitalitecN10122
Dissection forceps CarpentierDelacroix-ChevalierDC13110-28 
Scissors MetzenbaumDelacroix-ChevalierB351751
Needle holder RyderDelacroix-ChevalierDC51130-20 
Dissection forceps DeBakeyDelacroix-ChevalierDC12000-21 
Lung retractorDelacroix-ChevalierB803990
Allis clampDelacroix-ChevalierDC45907-25 
O’Shaugnessy DissectorDelacroix-ChevalierB60650
18 blade knifeDelacroix-ChevalierB130180
11 blade knifePremiere9311-2PK
Leriche haemostatic clampDelacroix-ChevalierB86555
Data analysis
Mann-Whitney and Chi-square testsGraphPadPrism 7

References

  1. Supino, P. G., Borer, J. S., Preibisz, J., Bornstein, A. The epidemiology of valvular heart disease: a growing public health problem. Heart. Fail. Clin. 2 (4), 379-393 (2006).
  2. Carabello, B. A., Paulus, W. J. Aortic stenosis. The Lancet. 373 (9667), 956-966 (2009).
  3. Bonow, R. O., et al.

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Tags

Central Aortic CannulationMinimally Invasive SurgeryCardiac CT MeasurementsPercutaneous Femoral AccessPurse String SuturingValve Prosthesis ImplantationPostoperative Outcomes