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JoVE Journal
Immunology and Infection

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与预先定义的T细胞受体特异性Transnuclear小鼠对弓形虫获得通过体细胞核移植
 
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与预先定义的T细胞受体特异性Transnuclear小鼠对弓形虫获得通过体细胞核移植

Article DOI: 10.3791/2168-v 13:37 min September 30th, 2010
September 30th, 2010

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Summary

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Click here for the English version.

我们证明,在这里,通过体细胞核移植(SCNT)后生重新编程可以作为一个工具来生成与预先定义的T细胞受体(TCR)特异性的小鼠模型使用。这些transnuclear小鼠表达​​内源性启动子的控制下的内源性轨迹相应的TCR。

Tags

体细胞核移植,第43期,发育生物学,免疫学,TCR,BCR,小鼠模型,transnuclear
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