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Multi-Photonen-Imaging der Tumorzellinvasion in einem orthotopen Mausmodell des oralen Plattenepithelkarzinoms
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Multi-Photonen-Imaging der Tumorzellinvasion in einem orthotopen Mausmodell des oralen Plattenepithelkarzinoms

Article DOI: 10.3791/2941 • 12:03 min
July 25th, 2011 •
1, 1, 1, 2, 3, 1
1Department of Neurobiology and Anatomy, Program in Cancer Cell Biology, Mary Babb Randolph Cancer Center, West Virginia University, 2Sensory Neuroscience Research Center, West Virginia University, 3Departments of Otolaryngology and Physiology, Center for Neuroscience, West Virginia University

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July 25th, 2011

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Einen umfassenden Überblick über die Techniken bei der Erzeugung von einem Maus-Modell von Mundkrebs und quantitative Überwachung der Tumorinvasion in die Zunge durch Multi-Photonen-Mikroskopie markierter Zellen beteiligt wird vorgestellt. Dieses System kann als eine nützliche Plattform für die molekulare Beurteilung und Wirksamkeit von Medikamenten von anti-invasive Verbindungen dienen.

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