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Neuroscience
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大人のラットの特定の脳領域の興奮毒性病変に対する定位手術
JoVE Journal
Neuroscience
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JoVE Journal
Neuroscience
Stereotaxic Surgery for Excitotoxic Lesion of Specific Brain Areas in the Adult Rat
Please note that all translations are automatically generated.
Click here for the English version.
大人のラットの特定の脳領域の興奮毒性病変に対する定位手術
DOI:
10.3791/4079-v
•
12:45 min
•
July 19, 2012
•
Elizabeth D. Kirby
,
Kelly Jensen
,
Ki A. Goosens
,
Daniela Kaufer
4
1
Helen Wills Neuroscience Institute
,
University of California Berkeley
,
2
Office of Laboratory Animal Care
,
University of California Berkeley
,
3
McGovern Institute for Brain Research & The Department of Brain and Cognitive Science
,
Massachusetts Institute of Technology
,
4
Integrative Biology Department
,
University of California Berkeley
Chapters
00:05
Title
01:11
Preparation of the Pump and Stereotax
03:26
Preparing the Rat for Surgery
04:36
Creating the Surgical Window
05:16
Leveling the Skull and Creating the Pilot Hole
07:13
Infusion of Neurotoxin
09:03
Closing the Incision
10:00
Results: Effects of the Cytotoxic Lesion
12:17
Conclusion
Summary
Automatic Translation
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Automatic Translation
定位座標を使用して、興奮性毒を注入することにより、特定の脳領域の対象とアブレーション(s)は記載されています。この手法はまた、ラット脳内に他の化学物質の注入に適応することができます。
Tags
Stereotaxic Surgery
Excitotoxic Lesion
Specific Brain Areas
Adult Rat
Localized Ablation
Electrolytic Lesions
Inducible Genetic Techniques
Cell-type Specific Promoters
Stereotaxic Infusion
Excitotoxin
N-methyl-D-aspartate (NMDA)
Basolateral Amygdala Complex
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