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JoVE Journal
Immunology and Infection
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Granulocyt-afhængig autoantistof-induceret vabler
 
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Granulocyt-afhængig autoantistof-induceret vabler

Article DOI: 10.3791/4250
October 12th, 2012

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Summary October 12th, 2012

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I dyremodellen beskrevet i vores foreliggende arbejde, oprenset IgG-antistoffer mod en strækning på 200 aminosyrer (aa 757-967) af kollagen VII injiceres gentagne gange i mus gengiver blærer fænotype såvel som histo-og immunpatologiske karakteristiske for menneskers epidermolysis bullosa acquisita (EBA)

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