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Intranasal administration af CNS Therapeutics at vågne mus
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Intranasal administration af CNS Therapeutics at vågne mus

Article DOI: 10.3791/4440-v • 07:15 min • April 8th, 2013
April 8th, 2013 •
1, 1, 1, 1
1Alzheimer’s Research Center at Region’s Hospital, HealthPartners Institute for Education and Research

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Fremgangsmåde til intranasal administration af lægemidler til vågne mus med henblik på målretning hjernen er beskrevet. Denne metode giver mulighed for gentagne doser over lange perioder med intranasal administration af lægemiddel uden bedøvelse, og næse-til-hjerne levering med minimal systemisk eksponering.

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Medicin Biomedical Engineering Neuroscience anatomi fysiologi Bioengineering neurobiologi farmakologi Intranasal nasal vågen mus drug delivery hjerne målretning CNS mus akklimatisering dyremodel terapi kliniske teknikker
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