A subscription to JoVE is required to view this content.
体外红血细胞溶血含量的生物大分子药物的细胞内交货的评价的pH响应Endosomolytic代理
The JoVE video player is compatible with HTML5 and Adobe Flash. Older browsers that do not support HTML5 and the H.264 video codec will still use a Flash-based video player. We recommend downloading the newest version of Flash here, but we support all versions 10 and above.
If that doesn't help, please let us know.
Unable to load video. Please check your Internet connection and reload this page. If the problem continues, please let us know and we'll try to help.
An unexpected error occurred. Please check your Internet connection and reload this page. If the problem continues, please let us know and we'll try to help.
Click here for the English version
Article
DOI:
10.3791/50166-v
•
11:13 min
•
March 9th, 2013
体外红血细胞溶血含量的生物大分子药物的细胞内交货的评价的pH响应Endosomolytic代理
March 9th, 2013
•
Brian C. Evans*1,2, Christopher E. Nelson*1,2, Shann S. Yu*1,2, Kelsey R. Beavers2,3, Arnold J. Kim1, Hongmei Li1,2, Heather M. Nelson4, Todd D. Giorgio1,2,5,6, Craig L. Duvall1,2
1Department of Biomedical Engineering, Vanderbilt University, 2Vanderbilt Institute for Nanoscale Science & Engineering, Vanderbilt University, 3Interdisciplinary Materials Science Program, Vanderbilt University, 4Monroe Carell Jr. Children's Hospital, Vanderbilt University Medical Center, 5Department of Chemical & Biomolecular Engineering, Vanderbilt University, 6Department of Cancer Biology, Vanderbilt University
* These authors contributed equally
Chapters
Summary
Please note that all translations are automatically generated.
Click here for the English version.
溶血试验可作为一种快速,高通量筛选,药物传递系统的细胞相容性和内货物配送endosomolytic活动的。该试验测量作为环境pH值的函数的红细胞膜的破坏。