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原正畸胶质血异草回顾渗透生长和同源脱氢酶 I 突变
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JoVE Journal Medicine
Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
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原正畸胶质血异草回顾渗透生长和同源脱氢酶 I 突变

DOI:
10.3791/50865-v

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09:43 min

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January 14, 2014

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, , ,
1Department of Neurology,Vanderbilt University Medical Center, 2Vanderbilt Ingram Cancer Center,Vanderbilt University Medical Center, 3Neurology Service,Veteran Affairs TVHS

Chapters

  • 00:05Title
  • 01:49Preparation of Tumor Cell Suspension
  • 04:41Intracranial Transplantation
  • 06:22Tumor Harvesting
  • 07:25Results: Tumor Growth after Grafting
  • 09:15Conclusion

Summary

Automatic Translation

Automatic Translation

恶性胶质瘤是一组具有明显临床和分子特征的高度渗透性胶质肿瘤的异质性群体。原位矫形异种格拉夫特在前科动物模型中重新概括恶性胶质瘤亚型的组织病理学和分子特征。

Tags

GliomaXenograftOrthotopicInfiltrative GrowthIsocitrate DehydrogenaseMalignant GliomaWHO Grade IIIWHO Grade IVPrimary XenograftTumor TransplantationImmunocompromised MiceTumor DissociationSurgical Procedure

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