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En ortotopisk musemodel for Human Prostata Cancer metastaser
JoVE Journal
Medicine
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JoVE Journal Medicine
An Orthotopic Murine Model of Human Prostate Cancer Metastasis

En ortotopisk musemodel for Human Prostata Cancer metastaser

DOI:
10.3791/50873-v

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06:48 min

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September 18, 2013

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, ,
1Department of Medicine,Northwestern University, 2Robert H. Lurie Cancer Center,Northwestern University, 3Center for Molecular Innovation and Drug Discovery,Northwestern University

Chapters

  • 00:05Title
  • 01:32Orthotopic Implantation of Human Prostate Cancer Cells
  • 02:35Necropsy Procedures
  • 03:39Results: Identification and Quantification of Metastases in a Murine Human Pancreatic Cancer Model
  • 06:27Conclusion

Summary

Automatic Translation

Automatic Translation

Denne orthotopisk model af human prostatacancer giver mulighed for kvantificering af tumorstørrelse cirkulerende tumorceller, og dannelse af særskilte metastase til lungen. Som celler skal undslippe det primære organ, ind i blodet, og implantatet i et sekundært site, denne model reelt rekapitulerer scenariet i mennesker.

Tags

Prostate CancerOrthotopic ModelMetastasisPreclinical ModelCirculating Tumor CellsLung MetastasisTherapeutic Response

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