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Urinblæren Udspilning Evoked Visceromotor Responses som en model for blæresmerter i mus
JoVE Journal
Medicine
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JoVE Journal Medicine
Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
DOI:

11:46 min

April 27, 2014

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Chapters

  • 00:00Title
  • 02:49Surgical Implantation of Urinary Bladder Catheter and Wire Electrodes
  • 06:15Anesthesia Step Down
  • 06:43EMG Recording During Bladder Distention
  • 08:12Analysis of Raw EMG Traces
  • 10:08Results
  • 11:08Conclusion

Summary

Automatic Translation

Ca. 3 til 8.000.000 mennesker i USA lider af interstitiel cystitis / blære smertesyndrom (IC / BPS), en invaliderende tilstand karakteriseret dels ved bækkensmerter. For at undersøge nervesystemet bidrag til den tilstand, er en fysiologisk model af urinblæren smerte anvendes i mus og rotter.

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