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Immunology and Infection

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JoVE Journal Immunology and Infection
En mus Model for Patogen-induceret kronisk inflammation på lokale og systemiske websteder
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En mus Model for Patogen-induceret kronisk inflammation på lokale og systemiske websteder

Article DOI: 10.3791/51556-v • 09:52 min • August 8th, 2014
August 8th, 2014 •
*1, *1, 1, 1, 2, 1, 1, 1
1Department of Medicine, Section of Infectious Disease, Boston University School of Medicine, 2Department of Biophysics, Boston University School of Medicine
* These authors contributed equally

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Dyremodeller har vist sig at være uvurderlige værktøjer i fastlæggelsen vært og patogen specifikke mekanismer, der bidrager til udviklingen af ​​kronisk inflammation. Her beskriver vi en musemodel af oral infektion med det humane patogen Porphyromonas gingivalis og detaljeret metoder til at vurdere progressionen af inflammation på lokale og systemiske steder.

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Immunologi Pathogen-induceret kronisk inflammation;
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