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Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters
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JoVE Journal Chemistry
Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

DOI:
10.3791/52090-v

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09:43 min

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August 22, 2014

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,
1Department of Biomedical Engineering,University of Texas at Austin, 2Department of Imaging Physics,University of Texas M.D. Anderson Cancer Center

Chapters

  • 00:05Title
  • 01:15Synthesis of Primary Hybrid Magneto-plasmonic Nanoparticles
  • 03:21Hybrid Magneto-plasmonic Nanoclusters Synthesis and Size Separation
  • 05:15Conjugation of Monoclonal Antibodies to Nanoclusters
  • 07:46Results: Nanocluster Characterization
  • 08:59Conclusion

Summary

Automatic Translation

Automatic Translation

Here, we describe a protocol for synthesis of magneto-plasmonic nanoparticles with a strong magnetic moment and a strong near-infrared (NIR) absorbance. The protocol also includes antibody conjugation to the nanoparticles through the Fc moiety for various biomedical applications which require molecular specific targeting.

Tags

Keywords: Magneto-plasmonic NanoparticlesMagnetomotive ImagingCirculating Tumor CellsMultimodal Molecular ImagingPhotothermal TherapyOil-in-water MicroemulsionMagneticPlasmonicAntibody FunctionalizationFcFab

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