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原发性肿瘤和/或转移相关的临床前和治疗的临床开发的离体处理响应
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Medicine
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JoVE Journal Medicine
Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics

原发性肿瘤和/或转移相关的临床前和治疗的临床开发的离体处理响应

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08:29 min

October 02, 2014

DOI:

08:29 min
October 02, 2014

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Summary

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建立癌症细胞系和裸鼠已经癌症研究的中流砥柱,在过去的几十年。然而,最近的证据表明,治疗响应在很大程度上是通过肿瘤细胞微环境的影响。因此,我们开发了原发肿瘤标本进行药物开发目的的体外分析。

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