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清醒、无拘无束的小鼠静脉输液同时记录肾交感神经活动和血压的新方法。
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Novel Approach for Simultaneous Recording of Renal Sympathetic Nerve Activity and Blood Pressure with Intravenous Infusion in Conscious, Unrestrained Mice.
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清醒、无拘无束的小鼠静脉输液同时记录肾交感神经活动和血压的新方法。

DOI:
10.3791/54120-v

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11:08 min

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February 14, 2018

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,
1Department of Pediatrics,University of Alberta, 2Department of Physiology & Biophysics,University of Mississippi Medical Center, 3Mississippi Center for Obesity Research

Chapters

  • 00:04Title
  • 00:44Surgical Implantation of the RSNA Electrode
  • 03:58Implantation of Blood Pressure Radiotelemeter
  • 06:02Implantation and Exteriorization of the Jugular Venous Catheter
  • 07:45Sample Experimental Protocol and Validation of RSNA Signal
  • 08:40Results: Renal Sympathetic Nerve Activity (RSNA) in Conscious Mice
  • 10:10Conclusion

Summary

Automatic Translation

Automatic Translation

麻醉小鼠表现为非生理系统血压, 由于血压和自主神经系统之间的密切关系, 导致对自主语气有意义的评估。为此, 本文概述了在有意识小鼠中, 用静脉输液同时记录肾交感神经活动和血压的新方法。

Tags

Renal Sympathetic Nerve ActivityBlood PressureConscious MiceIntravenous InfusionSimultaneous RecordingNovel Surgical TechniqueAutonomic Tone AssessmentAnesthesia-freeUnrestrained MiceRenal Neurovascular BundleElectrode Placement

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