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A Murine Model of Arterial Restenosis: Technical Aspects of Femoral Wire Injury
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A Murine Model of Arterial Restenosis: Technical Aspects of Femoral Wire Injury

A Murine Model of Arterial Restenosis: Technical Aspects of Femoral Wire Injury

DOI:
10.3791/52561-v

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06:42 min

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March 10, 2015

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, , , , , , , , ,
1Department of Surgery,University of Wisconsin School of Medicine and Public Health

Chapters

  • 00:05Title
  • 01:24Skin Incision and Exposure of Femoral Artery and Branches
  • 03:19Creating Wire Injury
  • 05:22Results: Neointima Foundation from Wire Injury of Femoral Artery
  • 06:20Conclusion

Summary

Automatic Translation

Automatic Translation

The mouse femoral artery wire injury model of restenosis is technically challenging. In this protocol we show the key technical details essential for successfully performing wire injury to induce consistent neointima for studies of restenosis.

Tags

Keywords: Arterial RestenosisFemoral Wire InjuryMurine ModelCardiovascular DiseaseAtherosclerosisAngioplastyNeointimal PlaqueVascular InterventionEndotheliumVessel WallSurgical Technique

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