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Kirurgisk angiogenese i svin Tibial Allotransplantation: en ny stor animalsk knogle vaskulariserede sammensatte Allotransplantation Model
JoVE Journal
Medicine
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JoVE Journal Medicine
Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
DOI:

10:31 min

August 13, 2017

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Chapters

  • 00:00Title
  • 00:16Introduction
  • 01:40Basic Principles of the Surgical Procedure
  • 03:18Presurgical Preparations
  • 03:53Harvest of a Vascularized Tibial Bone Segement (Bone VCA)
  • 06:24Orthotopic Tibial Bone VCA Reconstruction
  • 07:23Central Venous Catheter Placement
  • 07:54Postoperative Treatment and Follow Up
  • 08:46Results
  • 09:51Conclusion

Summary

Automatic Translation

I øjeblikket afhænger alle slags vaskulariserede sammensatte allotransplantation lang-sigt-immunosuppression, svært ved at støtte for ikke-liv-kritiske indikationer. Vi præsenterer en ny svin tibial VCA model, der kan bruges til at studere knogle VCA og demonstrere brugen af kirurgiske angiogenese at opretholde knogle levedygtighed uden brug af langsigtede immun-graduering.

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