A subscription to JoVE is required to view this content. Sign in or start your free trial.
1Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation (VCA) Laboratory,Johns Hopkins University School of Medicine, 2Department of Visceral, Transplant and Thoracic Surgery,Innsbruck Medical University, 3Center for Vascularized Composite Allotransplantation, Department of Plastic and Reconstructive Surgery,Chang Gung Memorial Hospital and School of Medicine, 4Department of General, Visceral and Transplant Surgery,Charite Berlin
Chapters
- 00:05Title
- 01:07Donor Limb Harvest
- 03:21Recipient Hind Limb Removal and Implantation
- 05:33Results: Representative Orthotopic Hind Limb Transplantation Analysis
- 06:16Conclusion
This novel model for orthotopic hind limb transplantation in the mouse, applying a non-suture cuff technique for super-microvascular anastomosis, provides a powerful tool for in vivo mechanistic immunological research related to vascularized composite allotransplantation (VCA).
