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干粉和药品的雾化吸入气雾剂递送小鼠使用鼻只曝光系统
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
Please note that all translations are automatically generated.
Click here for the English version.
干粉和药品的雾化吸入气雾剂递送小鼠使用鼻只曝光系统
DOI:
10.3791/55454-v
•
07:28 min
•
April 06, 2017
•
Jonathan E. Phillips
,
Xuxia Zhang
,
James A. Johnston
1
Inflammation Research
,
Amgen
Chapters
00:05
Title
00:57
Dry Powder and Nebulized Liquid Aerosol Generation
02:46
Aerosol Exposure Experimental Setup and Delivery
05:28
Results: Representative Effects of Real Time Aerosol Delivery
06:51
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
本文所描述的吸入单元可以产生,样品表征和在啮齿类动物的肺中均匀地沉积的药物气雾剂。这使得临床前确定的有效性和沉积于肺部药物剂量的安全性的;关键数据,使临床吸入药物的发展。
Tags
Dry Powder
Nebulized Aerosol
Inhalation
Pharmaceuticals
Mice
Nose-only Exposure System
Aerosol Generation
Jet Mill
Micronized Particles
Wright Dust Feed
Dry Powder Aerosol Generator
Nebulized Liquid Aerosol
Syringe Pump
Jet Nebulizer
Pre-separator
Absolute Filter Holder
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