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使用径向水痕迷宫评估外伤性脑损伤小鼠模型中的空间记忆障碍
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JoVE Journal Behavior
Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze
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使用径向水痕迷宫评估外伤性脑损伤小鼠模型中的空间记忆障碍

DOI:
10.3791/55986-v

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06:09 min

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July 17, 2017

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, , , , ,
1Department of Radiology,University of Washington, 2Department of Radiology,University of Utah, 3Geriatric Research Education and Clinical Center (GRECC),VA Puget Sound

Chapters

  • 00:05Title
  • 00:54Preparing the Radial Water Tread Maze
  • 02:11Testing Protocol
  • 04:21Results: Using the Radial Water Maze to Measure Learning in TBI Mice
  • 05:33Conclusion

Summary

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Automatic Translation

在这里，我们提出了一个不需要游泳的认知的小鼠特异性测试方案。该测试可用于成功地区分受控皮质冲击引起的创伤性脑损伤小鼠与假手术对照。

Tags

Spatial MemoryRadial Water Tread MazeTraumatic Brain InjuryMouse ModelCognitive TestingMorris Water MazeEscape BoxVisual CuesWater TemperatureLightingTrial Duration

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