Journal
/
Bioengineering
/
An Efficient and Reproducible Protocol for Distraction Osteogenesis in a Rat Model Leading to a Functional Regenerated Femur
JoVE Journal
Bioengineering
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Bioengineering
An Efficient and Reproducible Protocol for Distraction Osteogenesis in a Rat Model Leading to a Functional Regenerated Femur

An Efficient and Reproducible Protocol for Distraction Osteogenesis in a Rat Model Leading to a Functional Regenerated Femur

DOI:
10.3791/56433-v

•

09:26 min

•

October 23, 2017

•

, , , , , , ,
1CNRS, ISM, Inst Movement Sci,Aix Marseille Univ, 2Sainte-Marguerite Hospital, Institute for Locomotion, Department of Orthopaedics and Traumatology,APHM, 3Sainte-Marguerite Hospital, Institute for Locomotion, Department of Peadiatric Orthopaedics,APHM, 4Ecole centrale de Marseille, 5Faculté de Pharmacie,Laboratoire de Biochimie, 6Service Central de la Qualité et de l’Information Pharmaceutiques,APHM

Chapters

  • 00:05Title
  • 01:10Femur Explant Fixator Implantation and Osteotomization
  • 04:30Distraction and Femur Resection
  • 06:05Results: Representative Femur Regeneration Analyses
  • 08:06Conclusion

Summary

Automatic Translation

Automatic Translation

This study describes a reproducible and detailed protocol using a newly developed external fixator for distraction osteogenesis (DO) in a femoral rat model which permits physiological weight-bearing by the animal after removal of the external fixator.

Tags

Keywords: Distraction OsteogenesisRat ModelFemur RegenerationExternal FixatorBone LengtheningBone DefectBone RepairBone RegenerationReproducible ProtocolSurgical Procedure

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/56433?article_type=v

Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement
check_url/56433?article_type=v

Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves
check_url/56433?article_type=v

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
check_url/56433?article_type=v

Use of a Rat Model to Study Ventral Abdominal Hernia Repair
check_url/56433?article_type=v

Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair
check_url/56433?article_type=v

A Method to Estimate Cadaveric Femur Cortical Strains During Fracture Testing Using Digital Image Correlation
check_url/56433?article_type=v

An Experimental and Finite Element Protocol to Investigate the Transport of Neutral and Charged Solutes across Articular Cartilage
check_url/56433?article_type=v

Development of an Electrochemical DNA Biosensor to Detect a Foodborne Pathogen
check_url/56433?article_type=v

Rodent Behavioral Testing to Assess Functional Deficits Caused by Microelectrode Implantation in the Rat Motor Cortex
check_url/56433?article_type=v

A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat

Read Article