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JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Opbygge en høj overførselshastighed Screening Platform til at vurdere heterogenitet af HER2 genet forstærkning i brystkræft
 
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Opbygge en høj overførselshastighed Screening Platform til at vurdere heterogenitet af HER2 genet forstærkning i brystkræft

Article doi: 10.3791/56686
December 5th, 2017 •
1, 1,2, 1,3, 1,2, 4, 5, 1, 4, 1, 1,6
1Division of Pathology, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 2School of Medicine, University of Milan, 3School of Biology, University of Pavia, 4Division of Breast Surgery, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, 5Division of Medical Oncology, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, 6Department of Biomedical, Surgical, and Dental Sciences, University of Milan

Summary
Automatic Translation
December 5th, 2017

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Heterogen fordeling af HER2-positive celler kan observeres i en delmængde af brystkræft og genererer kliniske dilemmaer. Her introducerer vi en pålidelig og omkostningseffektiv protokol for at definere, kvantificere og sammenligne HER2 intra-tumor genetiske heterogenitet i en lang række uensartet forarbejdede brystkræft.

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