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Pilocarpin Model af frontal-lap epilepsi og EEG overvågning ved hjælp af Radiotelemetry System i mus
JoVE Journal
Medicine
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JoVE Journal Medicine
The Pilocarpine Model of Temporal Lobe Epilepsy and EEG Monitoring Using Radiotelemetry System in Mice
DOI:

10:08 min

February 27, 2018

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Chapters

  • 00:04Title
  • 00:50Status Epilepticus (SE) Induction
  • 03:24Implantation Surgery for Video-EEG Monitoriing
  • 06:19Video and EEG Monitoring and Analysis
  • 08:01Results: Successful SE Can Induce Hippocampal Cell Death and SRS
  • 09:03Conclusion

Summary

Automatic Translation

Dette manuskript beskriver en metode af inducerende status epilepticus ved systemisk pilocarpin injektion og overvågning spontan tilbagevendende anfald hos levende dyr brug af en trådløs telemetri video og elektroencefalografi system. Denne protokol kan udnyttes til at studere de patofysiologiske mekanismer for kronisk epilepsi, epileptogenesis og akut anfald.

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