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Journal
/
Cancer Research
/
神经入侵的
体内小
鼠坐骨神经模型
JoVE Journal
Cancer Research
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JoVE Journal
Cancer Research
An
In Vivo
Murine Sciatic Nerve Model of Perineural Invasion
Please note that all translations are automatically generated.
Click here for the English version.
神经入侵的
体内小
鼠坐骨神经模型
DOI:
10.3791/56857-v
•
09:55 min
•
April 23, 2018
•
Sylvie Deborde*
1
,
Yasong Yu*
1
,
Andrea Marcadis
,
Chun-Hao Chen
,
Ning Fan
,
Richard L. Bakst
,
Richard J. Wong
1
Department of Surgery
,
Memorial Sloan Kettering Cancer Center
,
2
Molecular Cytology Core Facility
,
Memorial Sloan Kettering Cancer Center
,
3
Department of Radiation Oncology
,
Mount Sinai Hospital
Chapters
00:05
Title
01:25
Preparation of Cultured Cancer Cells
02:35
Preparation of Mouse and Surgery
06:06
Sciatic Nerve Extraction
07:24
Nerve Processing and Quantification
08:26
Results: H&E Longitudinal Sections of Sciatic Nerves Injected with Panc02H7 Cancer Cells in Wild Type and NCAM KO Mice
09:10
Conclusion
Summary
Automatic Translation
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Automatic Translation
我们描述了一个
体内小
鼠神经入侵的模型, 注射自体胰腺癌细胞进入坐骨神经。该模型允许定量的神经入侵程度, 并支持调查的细胞和分子机制的神经入侵。
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