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Chapters
- 00:05Title
- 01:25Preparation of Cultured Cancer Cells
- 02:35Preparation of Mouse and Surgery
- 06:06Sciatic Nerve Extraction
- 07:24Nerve Processing and Quantification
- 08:26Results: H&E Longitudinal Sections of Sciatic Nerves Injected with Panc02H7 Cancer Cells in Wild Type and NCAM KO Mice
- 09:10Conclusion
Vi beskriver en i vivo murine model af perineural invasion ved at indsprøjte syngeneic bugspytkirtelkræftceller i iskiasnerven. Modellen giver mulighed for kvantificering af omfanget af nerve invasion, og understøtter undersøgelse af de cellulære og molekylære mekanismer af perineural invasion.
