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Journal / Neuroscience / A Volumetric Method for Quantification of…
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Neuroscience
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JoVE Journal Neuroscience
A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
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A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

Article DOI: 10.3791/57997-v • 08:13 min • July 28th, 2018
July 28th, 2018 •
*1, *1, *1, 2, 3, 2, 1, 4
1Department of Neurosurgery, Medical Center of the Johannes Gutenberg - University, 2Department of Neuroradiology, Medical Center of the Johannes Gutenberg - University, 3Platform for Biomaterial Research, Medical Center of the Johannes Gutenberg - University, 4Department of Anesthesiology, Medical Center of the Johannes Gutenberg - University
* These authors contributed equally

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Summary
Automatic Translation

The goal of this article is to present a method that allows a 3-dimensional reconstruction of the cerebrovascular tree in mice after micro computed tomography and determination of volumes of entire vessel segments that can be used to quantify cerebral vasospasm in murine models of subarachnoid hemorrhage.

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Cerebral Vasospasm Murine Model Subarachnoid Hemorrhage Quantification Transcardiac Perfusion Endovascular Casting Radiopaque Casting Agent Microcomputer Tomography Image Data Processing Intracranial Vascular Tree Reconstruction Vessel Segment Volumes Objective Measure Endovascular Filament Perforation Isoflurane Anesthesia External Carotid Artery Preparation Intra Cranial Pressure Anesthesia Level Transcardiac Perfusion
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