Journal
/
Medicine
/
Implantation of hiPSC-derived Cardiac-muscle Patches after Myocardial Injury in a Guinea Pig Model
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Implantation of hiPSC-derived Cardiac-muscle Patches after Myocardial Injury in a Guinea Pig Model

Implantation of hiPSC-derived Cardiac-muscle Patches after Myocardial Injury in a Guinea Pig Model

DOI:
10.3791/58810-v

•

07:03 min

•

March 18, 2019

•

, , , , , , , ,
1Department of Cardiovascular Surgery,University Heart Center Hamburg, 2partner site Hamburg/Kiel/Lübeck,German Centre for Cardiovascular Research (DZHK), 3Department of Experimental Pharmacology and Toxicology, Cardiovascular ResearchCenter,University Medical Center Hamburg-Eppendorf

Chapters

  • 00:04Title
  • 00:33Transthoracic Echocardiography
  • 01:27Myocardial Infarction Induction
  • 04:10Engineered Heart Tissue (EHT) Implantation
  • 05:21Results: Representative Human Engineered Heart Tissue (hEHT) Patch Analyses
  • 06:05Conclusion

Summary

Automatic Translation

Automatic Translation

Here we present a protocol for the induction of left ventricular cryoinjury followed by the implantation of a cardiac muscle patch, derived from human iPS-cell cardiomyocytes in a guinea pig model.

Tags

Keywords: HiPSC-derived Cardiac-muscle PatchesMyocardial InjuryGuinea Pig ModelCryoinfarction ModelEchocardiographyTracheal IntubationThoracotomyLeft Ventricular Cryoinjury

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/58810?article_type=v

Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
check_url/58810?article_type=v

A Murine Model of Myocardial Ischemia-reperfusion Injury through Ligation of the Left Anterior Descending Artery
check_url/58810?article_type=v

Murine Model of Femoral Artery Wire Injury with Implantation of a Perivascular Drug Delivery Patch
check_url/58810?article_type=v

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
check_url/58810?article_type=v

A Guide to Generating and Using hiPSC Derived NPCs for the Study of Neurological Diseases
check_url/58810?article_type=v

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
check_url/58810?article_type=v

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
check_url/58810?article_type=v

Cochlear Implantation in the Guinea Pig
check_url/58810?article_type=v

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
check_url/58810?article_type=v

Model of Ischemic Heart Disease and Video-Based Comparison of Cardiomyocyte Contraction Using hiPSC-Derived Cardiomyocytes

Read Article