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February 10, 2015
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We describe a surgical technique that produces wire injury in the femoral artery of mice to induce neointimal hyperplasia to serve as a model testing system for the perivascular delivery of therapeutic compounds for the inhibition of restenosis.
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Cite this Article
Le, V., Johnson, C. G., Lee, J. D., Baker, A. B. Murine Model of Femoral Artery Wire Injury with Implantation of a Perivascular Drug Delivery Patch. J. Vis. Exp. (96), e52403, doi:10.3791/52403 (2015).
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