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Fabrikasjon av amyloid-β-sekresjon alginat Mikroperler for bruk i modellering Alzheimers sykdom
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Fabrikasjon av amyloid-β-sekresjon alginat Mikroperler for bruk i modellering Alzheimers sykdom

Article DOI: 10.3791/59597-v • 06:52 min • July 6th, 2019
July 6th, 2019 •
1, 2, 1, 1
1Division of Pharmacy and Optometry, School of Health Studies, Faculty of Biology, Medicine and Health, University of Manchester, 2Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester

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Denne protokollen illustrerer en celle innkapsling metode ved rask fysisk gelation av alginat til nakkens celler. Innhentet mikroperler tillate kontrollert og vedvarende sekresjon av amyloid-β over tid og kan brukes til å studere effekten av utskilles amyloid-β in vitro og in vivo-modeller.

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Biologi Alzheimers sykdom amyloid Aβ hydrogeler alginat innkapsling 3D in vitro-modeller kontrollert utgivelse
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