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JoVE Journal
Immunology and Infection

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Adoptivimmunterapi af iNKT-celler i glucose-6-fosfatisomerase (G6PI)-Induceret RA-mus
 

Adoptivimmunterapi af iNKT-celler i glucose-6-fosfatisomerase (G6PI)-Induceret RA-mus

Article doi: 10.3791/60048
January 31st, 2020

Summary January 31st, 2020

Please note that all translations are automatically generated.

Click here for the English version.

Denne protokol bruger G6PI blandede peptider til at konstruere leddegigt modeller, der er tættere på den menneskelige leddegigt i CD4+ T celler og cytokiner. Høj renhed invariant naturlige dræber T-celler (hovedsagelig iNKT2) med specifikke fænotyper og funktioner blev opnået ved in vivo induktion og in vitro rensning for adoptivimmunterapi.

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