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免疫细胞衍生细胞外囊泡的表征及研究功能对细胞环境的影响
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Characterization of Immune Cell-derived Extracellular Vesicles and Studying Functional Impact on Cell Environment
DOI:

10:09 min

June 02, 2020

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Chapters

  • 00:05Title
  • 01:01Isolation of EVs
  • 02:54Characterization of EVs
  • 07:07Results: Analysis of Isolated Extracellular Vesicles
  • 09:16Conclusion

Summary

Automatic Translation

本报告强调了从微胶质或血液巨噬细胞分离细胞外囊泡(EV)的时间顺序要求。微胶质衍生的EV被评价为神经外生长的调节器,而血液巨噬细胞衍生的EV在体外检测中控制C6胶质瘤细胞入侵时被研究。目标是更好地了解这些EV功能作为免疫中介器在特定微环境中。

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