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JoVE Journal
Neuroscience

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Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro
 

Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro

Article DOI: 10.3791/2910
June 13th, 2011

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Summary June 13th, 2011

Migraine and its transformation to chronic migraine are immense healthcare burdens in need of improved treatment options. We seek to define how neural immune signaling modulates the susceptibility to migraine, modeled in vitro using spreading depression in hippocampal slice cultures, as a means to develop novel therapeutic targets.

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