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JoVE Journal Medicine
Modelo suíno de aneurisma aórtica abdominal infra-renal
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Modelo suíno de aneurisma aórtica abdominal infra-renal

Article DOI: 10.3791/60169-v • 11:13 min • November 21st, 2019
November 21st, 2019 •
1, 1, 1, 1, 1, 1, 1, 2, 3, *1, *1,4, *3
1Department of Surgery, University of Virginia School of Medicine, 2Department of Surgery, Ochsner Medical Center, 3Department of Surgery, University of Florida, 4The Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine
* These authors contributed equally

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Este modelo novo cria aneurismas abdominais infra-renais robustos no suíno usando uma combinação de angioplastia do balão, perfusão elastase/collagenase, aplicação tópica da elastase, e administração do composto oral β-aminopropionitrile, que interfere com a cruz-ligação do colágeno.

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Medicina Edição 153 Doençacardiovascular aneurismas da Aorta citocinas imunohistoquímica macrófagos inflamação
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