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JoVE Journal
Immunology and Infection

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使用荧光抗生素探针对细菌耐药性的可视化
 
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使用荧光抗生素探针对细菌耐药性的可视化

Article DOI: 10.3791/60743-v 08:23 min March 2nd, 2020
March 2nd, 2020

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Summary

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Click here for the English version.

荧光标记的抗生素是强大的工具,可用于研究抗菌素耐药性的多个方面。本文介绍了荧光标记抗生素的制备及其在细菌中抗生素耐药性研究中的应用。探针可用于通过分光光度测定法、流式细胞测定和显微镜研究细菌抗性机制(例如,排泄物)。

Tags

免疫学和感染,第157期,抗生素,耐药性,细菌,排泄物,荧光,显微镜
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PLAYLIST

Pharmaceutical Chemistry Formulation of introductory drug. Generic and Ethical Drugs Pre-formulation: Introduction, influencing factors
Active SAR Functional Groups (Pharmacopoeial Colloids: Difference between Colloidal Solutions, Colloid Types) Stability Emulsions: Types of Emulsions (Selection of HLB Composition and Properties, Milk Calculations The quantitative relationship between the drug's structure and its activity (QSAR) (types of surfactants, composition and properties, stability enhancement methods, substances) - Drug Design Strategies 8 Optimize interactions with the target site
Opiate painkillers (nsaids) nonsteroidal anti-bacterial (antibacterial drugs) Need for controlled release drugs: Defined release versus controlled release, drug controlled release types, diffusion-based systems and transdermal systems Design and Synthesis of Drugs Microcapsulation Peptides for Drugs: Microcapsules
Preparation of tablets by the wet granulation method and the examination of the physicochemical properties of the tablets

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