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JoVE Journal
Immunology and Infection

This content is Open Access.

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
 

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Article doi: 10.3791/53084
October 5th, 2015

Summary October 5th, 2015

Human tuberculosis infection is a complex process, which is difficult to model in vitro. Here we describe a novel 3D human lung tissue model that recapitulates the dynamics that occur during infection, including the migration of immune cells and early granuloma formation in a physiological environment.

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