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Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology
Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology
JoVE Journal
Medicine
Author Produced
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JoVE Journal Medicine
Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology

Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology

15,787 Views

12:36 min

March 14, 2020

DOI:

12:36 min
March 14, 2020

15761 Views
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Summary

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This protocol provides a simple and reliable method for the production of viable precision-cut liver slices from mice. The ex vivo tissue samples can be maintained under laboratory tissue culture conditions for multiple days, providing a flexible model to examine liver pathobiology.

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