Journal
/
/
乳腺癌临床前模型乳腺肿瘤的矫形移植
JoVE Journal
Cancer Research
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Cancer Research
Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer
DOI:

07:45 min

May 18, 2020

, , , , ,

Chapters

  • 00:04Introduction
  • 01:22Cryopreserved Mammary Tumor Fragment Preparation
  • 02:23Fresh Mammary Tumor Sample Collection and Preparation
  • 03:28Surgical Preparation
  • 04:04Tumor Fragment Transplantation
  • 06:26Results: Representative Transplant Tumor Characterization
  • 06:54Conclusion

Summary

Automatic Translation

患者衍生异种移植(PDX)模型和可移植的基因工程小鼠模型忠实地概括了人类疾病,是基础和转化乳腺癌研究的首选模型。在这里,一种方法被描述为正位移植乳房肿瘤片段到乳腺脂肪垫研究肿瘤生物学和评估药物反应。

Related Videos

Read Article