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JoVE Journal Developmental Biology
Vasculaire casting van volwassen en vroege postnatale muislongen voor micro-CT-beeldvorming
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Vasculaire casting van volwassen en vroege postnatale muislongen voor micro-CT-beeldvorming

Article DOI: 10.3791/61242-v • 09:00 min • June 20th, 2020
June 20th, 2020 •
1, 1, 1, 2, 1, 1, 3, 1
1Translational Vascular Medicine Branch, National Heart Lung and Blood Institute, National Institutes of Health, 2Mouse Imaging Facility, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 3Division of Pediatric Surgery, Department of Surgery, University of North Carolina at Chapel Hill

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Het doel van deze techniek is ex vivo visualisatie van longslagaderlijke netwerken van vroege postnatale en volwassen muizen door middel van longinflatie en injectie van een radio-ondoorzichtige polymeer-gebaseerde verbinding via de longslagader. Mogelijke toepassingen voor gegoten weefsels worden ook besproken.

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Ontwikkelingsbiologie Nummer 160 long micro computertomografie perfusie vasculair arteriële beeldvorming gegoten
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