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Cancer Research

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JoVE Journal Cancer Research
Modellering av primära bentumörer och benmetastaser med solid tumörtransplantatimplantation i ben
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Modellering av primära bentumörer och benmetastaser med solid tumörtransplantatimplantation i ben

Article DOI: 10.3791/61313-v • 06:53 min • September 9th, 2020
September 9th, 2020 •
1, 2, 2
1Department of Pathology and O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, 2Surgical Discovery Centre, Department of Veterinary Medicine, University of Cambridge

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Benmetastasmodeller utvecklar inte metastaser enhetligt eller med 100% förekomst. Direkt intraosseös tumörcellsinjektion kan resultera i embolisering av lungan. Vi presenterar vår teknik modellering primära bentumörer och benmetastaser med hjälp av solid tumörtransplantatimplantation i ben, vilket leder till reproducerbar engraftment och tillväxt.

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Denna månad i JoVE nummer 163 Ben tumör allograft metastaser kirurgi implantation
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