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Somministrazione di agenti alogenati in modelli suini di sindrome da distress respiratorio acuto tramite un dispositivo di tipo unità di terapia intensiva
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Somministrazione di agenti alogenati in modelli suini di sindrome da distress respiratorio acuto tramite un dispositivo di tipo unità di terapia intensiva

Article DOI: 10.3791/61644-v • 09:36 min • September 24th, 2020
September 24th, 2020 •
1,2, 1,2, 1,2, 1,2, 1,2, 2, 2, 2, 1, 1,2, 1, 3, 2,4, 1,2,5
1Department of Perioperative Medicine, CHU Clermont-Ferrand, 2GReD, CNRS, INSERM, Université Clermont Auvergne, 3GRC 29, AP-HP, DMU DREAM, Department of Anesthesiology and Critical Care, Pitié-Salpêtrière Hospital, Sorbonne University, 4Department of Biochemistry and Molecular Genetics, CHU Clermont-Ferrand, 5Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center

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Descriviamo un modello di sindrome da distress respiratorio acuto indotto da acido cloridrico (ARDS) in suinetti sottoposti a sedazione con agenti alogenati, isoflurano e sevoflurano, attraverso un dispositivo utilizzato per la sedazione in terapia intensiva inalatoria. Questo modello può essere utilizzato per studiare i meccanismi biologici degli agenti alogenati sulle lesioni polmonari e sulla riparazione.

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Medicina Numero 163 modello suino sevoflurano isoflurano agenti alogenati lesioni polmonari nuove terapie ARDS
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