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JoVE Journal
Neuroscience

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JoVE Journal Neuroscience
Cocultura di neuroni ganglionali retini di ratto axotomizzati con glia ensheathing olfattiva, come modello in vitro di rigenerazione assionale adulta
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Cocultura di neuroni ganglionali retini di ratto axotomizzati con glia ensheathing olfattiva, come modello in vitro di rigenerazione assionale adulta

Article DOI: 10.3791/61863-v
November 2nd, 2020 •
1,3, 1, 2, 1, 3
1Facultad de CC Experimentales, Universidad Francisco de Vitoria, 2Dept. Biomedical and Biotechnological Sciences, Section of Physiology, University of Catania, 3Dept. Anatomía, Histología y Neurociencia, Facultad de Medicina, Universidad Autónoma de Madrid

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November 2nd, 2020

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Presentiamo un modello in vitro per valutare la capacità neuroregenerativa olfattiva di glia (OEG), dopo la lesione neurale. Si basa su una cocultura di neuroni ganglionali della retina adulta assotomizzati (RGN) su monostrati OEG e sul successivo studio della rigenerazione assonale, analizzando marcatori assonali e somatodendritici RGN.

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