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Medicine
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模拟早期椎间盘疾病的发炎性、退行性器官培养模型。
JoVE Journal
Medicine
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JoVE Journal
Medicine
A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.
Please note that all translations are automatically generated.
Click here for the English version.
模拟早期椎间盘疾病的发炎性、退行性器官培养模型。
DOI:
10.3791/62100-v
•
05:46 min
•
February 14, 2021
•
Babak Saravi*
1,2
,
Gernot Lang*
2
,
Sibylle Grad
,
Mauro Alini
,
R. Geoff Richards
2
,
Hagen Schmal
,
Norbert Südkamp
,
Zhen Li
1
AO Research Institute Davos, Davos, Switzerland
,
2
Department of Orthopedics and Trauma Surgery, Medical Centre-Albert-Ludwigs-University of Freiburg, Faculty of Medicine
,
Albert-Ludwigs-University of Freiburg, Freiburg, Germany
Chapters
00:04
Introduction
00:38
Dissection of the Bovine Intervertebral Disc
02:27
IVD Culture and Loading
03:36
Intradiscal TNF-α Injection
04:13
Results: Assessment of Intervertebral Disc Degeneration Caused by Degenerative Loading, Limited Nutrition, and TNF-α Injection
04:59
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
该协议提出了一种新的实验模型的发炎,退化牛器官培养,以模拟早期椎间盘退化。
Tags
Intervertebral Disc Degeneration
Organ Culture Model
Bioreactor
Disc Culture
Disc Loading
Degenerative Disc Disease
In Vitro Model
Bovine Tail
Disc Height
Disc Diameter
Disc Microenvironment
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