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Behavior
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使用大鼠对象定位任务的主体内实验设计
JoVE Journal
Behavior
This content is Free Access.
JoVE Journal
Behavior
A Within-Subject Experimental Design using an Object Location Task in Rats
Please note that all translations are automatically generated.
Click here for the English version.
使用大鼠对象定位任务的主体内实验设计
DOI:
10.3791/62458-v
•
09:28 min
•
May 06, 2021
•
Gülberk Bayraktar*
1,2
,
Kristoffer Højgaard*
1,3
,
Luc Nijssen
4
,
Tomonori Takeuchi
5
1
Danish Research Institute of Translational Neuroscience (DANDRITE), Department of Biomedicine
,
Aarhus University
,
2
Universitätsklinikum Würzburg, Institut für Klinische Neurobiologie
,
3
Translational Neuropsychiatry Unit, Department of Clinical Medicine
,
Aarhus University
,
4
Faculty of Science
,
Radboud University
,
5
Center for Proteins in Memory – PROMEMO, Danish National Research Foundation, Department of Biomedicine
,
Aarhus University
Chapters
00:04
Introduction
00:44
Experimental Setup and Preparation of Distinct Contexts
02:02
Object Habituation
02:58
Empty Box Habituation
03:29
Context Habituation
04:24
Encoding Trial
05:25
Test Trial
06:15
Data Analysis
06:54
Results: Memory Performance After Strong and Weak Encoding
08:44
Conclusion
Summary
Automatic Translation
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Automatic Translation
此协议为使用同一组大鼠重复的对象定位任务提供了详细的步骤。弱而强的编码可以产生短期和长期的记忆。重复协议的灵活性可以通过节省时间和劳动力来促进涉及手术的研究。
Tags
Object Location Task
Spatial Memory
Spontaneous Exploration
Rodents
Within-subject Design
Arena
3D Spatial Cues
Habituation
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