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JoVE Journal
Cancer Research

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Rekonstruera humant retinoblastom in vitro
 
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Rekonstruera humant retinoblastom in vitro

Article DOI: 10.3791/62629-v 06:52 min October 11th, 2022
October 11th, 2022

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Summary

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Vi beskriver en metod för att generera humant retinoblastom (RB) genom att införa bialleliska RB1-mutationer i mänskliga embryonala stamceller (hESC). RB-cellinjer kan också framgångsrikt odlas med hjälp av den isolerade RB i en skål.

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Cancerforskning nummer 188
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