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Journal / Bioengineering / 用于疫苗接种目的的mRNA负载的聚（β-氨基酯）纳米颗粒的合成和表征…
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Bioengineering

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JoVE Journal Bioengineering
用于疫苗接种目的的mRNA负载的聚（β-氨基酯）纳米颗粒的合成和表征
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用于疫苗接种目的的mRNA负载的聚（β-氨基酯）纳米颗粒的合成和表征

Article DOI: 10.3791/62889-v • 08:27 min • August 13th, 2021
August 13th, 2021 •
1, 1, 1, 1, 1, 1, 1, 1
1Grup d’Enginyeria de Materials (Gemat), Institut Químic de Sarrià (IQS), Universitat Ramon Llull (URL)

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在这里，提出了一种基于聚（β-氨基酯）聚合物的mRNA纳米颗粒的简单方案，易于通过改变封装的mRNA进行定制。还描述了合成聚合物，纳米颗粒及其 体外 基本表征的工作流程。还增加了关于免疫接种的概念验证。

Tags

生物工程，第174期，mRNA负载，聚（β-氨基酯）聚合物，聚合物纳米颗粒，冷冻干燥，疫苗接种
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