Retinal Pathophysiological Evaluation in a Rat Model

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Medicine

JoVE Journal
Medicine
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JoVE Journal Medicine

Retinal Pathophysiological Evaluation in a Rat Model

DOI:

10.3791/63111-v

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09:11 min

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May 06, 2022

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Manisha Malani, Jayabalan Nirmal

¹Translational Pharmaceutics Research Laboratory (TPRL), Department of Pharmacy,Birla Institute of Technology & Science — Pilani, Hyderabad Campus

Chapters

00:09Introduction
01:11Retinal Histology
03:40Blood Retinal Barrier Breakdown Assay
05:15Fluorescence Angiography
07:09Representative Results
08:40Conclusion

Summary

Automatic Translation

Diabetic retinopathy is one of the leading causes of blindness. Histology, blood-retinal barrier breakdown assay, and fluorescence angiography are valuable techniques to understand the pathophysiology of the retina, which could further enhance the efficient drug screening against diabetic retinopathy.

Retinal Pathophysiological Evaluation in a Rat Model

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