3,204 Views
•
04:45 min
•
December 29, 2021
DOI:
Summary
Automatically generated
Here, a protocol for creating a central corneal epithelial abrasion wound in the mouse using a trephine and a blunt golf club spud is described. This corneal wound healing model is highly reproducible and is now being used to evaluate compromised corneal wound healing in the context of diseases.
Related Videos
07:53
Establishment of a Clinically Relevant Ex Vivo Mock Cataract Surgery Model for Investigating Epithelial Wound Repair in a Native Microenvironment
Related Videos
6541 Views
12:00
A Simplified Technique for Producing an Ischemic Wound Model
Related Videos
17260 Views
09:31
Investigating Scarless Tissue Regeneration in Embryonic Wounded Chick Corneas
Related Videos
1882 Views
07:28
Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Related Videos
20364 Views
06:46
Ex Vivo Corneal Organ Culture Model for Wound Healing Studies
Related Videos
11666 Views
07:10
Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium
Related Videos
3383 Views
12:36
A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
Related Videos
4527 Views
06:10
Three Strategies to Induce Neurotrophic Keratitis and Nerve Regeneration in Murine Cornea
Related Videos
1565 Views
08:19
Zebrafish Corneal Wound Healing: From Abrasion to Wound Closure Imaging Analysis
Related Videos
2836 Views
04:48
Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
Related Videos
259 Views
Read Article
Cite this Article
Akowuah, P. K., De La Cruz, A., Smith, C. W., Rumbaut, R. E., Burns, A. R. An Epithelial Abrasion Model for Studying Corneal Wound Healing. J. Vis. Exp. (178), e63112, doi:10.3791/63112 (2021).
Copy