Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Neuroscience / 使用光遗传学逆转大鼠的神经可塑性并抑制可卡因的寻找…
JoVE Journal
Neuroscience

A subscription to JoVE is required to view this content. Sign in or start your free trial.

JoVE Journal Neuroscience
使用光遗传学逆转大鼠的神经可塑性并抑制可卡因的寻找
3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
Journal (Neuroscience)
3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
Diffusion Imaging in the Rat Cervical Spinal Cord
Journal (Neuroscience)
Diffusion Imaging in the Rat Cervical Spinal Cord
 
Click here for the English version

使用光遗传学逆转大鼠的神经可塑性并抑制可卡因的寻找

Article DOI: 10.3791/63185-v • 09:43 min • October 5th, 2021
October 5th, 2021 •
1,2, 1, 1
1Department of Psychiatry, University of Pittsburgh, 2Department of Psychiatry, Rutgers University

Chapters

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

这里描述的方法概述了用于在大鼠行为相关回路中以光遗传学逆转可卡因诱导的可塑性的程序。丘脑-杏仁核突触的持续低频光刺激可诱发长期抑郁（LTD）。在经历可卡因的大鼠中 体内光遗传 诱导的LTD导致随后的线索动机药物寻求减弱。

Tags

神经科学，第176期，长期抑郁症，恢复，杏仁核，光遗传学，神经调控
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter