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Journal / Biology / Yetişkin Anofeller gambiae Sivrisineklerine…
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Yetişkin Anofeller gambiae Sivrisineklerine Etkili Oral RNA İnferferi (RNAi) Uygulaması
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Yetişkin Anofeller gambiae Sivrisineklerine Etkili Oral RNA İnferferi (RNAi) Uygulaması

Article DOI: 10.3791/63266-v • 07:48 min • March 1st, 2022
March 1st, 2022 •
1,2, 1, 3, 4,5, 5,6, 1, 5,7,8
1Division of Parasitic Diseases and Malaria, Entomology Branch, Centers for Disease Control and Prevention, 2Department of Entomology, Cornell University, 3Centro de Estudios en Biotecnologia, Universidad del Valle de Guatemala, 4Department of Cell Biology, Johns Hopkins School of Medicine, 5Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, 6Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health and Malaria Research Institute, 7Department of Cell Biology, Johns Hopkins School of Medicine, 8Biomedical Sciences Department, Idaho College of Osteopathic Medicine

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Caenorhabditis elegans'ta rutin olarak kullanılan RNA girişimi (RNAi) için bir dağıtım yöntemi olan bakteriler tarafından üretilen dsRNA'nın oral yoldan uygulanması, burada yetişkin sivrisineklere başarıyla uygulanmıştır. Yöntemimiz, enjeksiyon kullanmadan sağlam ters genetik çalışmalarına ve iletimi engelleyen vektör çalışmalarına izin verir.

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