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Vurdering af åben sandsynlighed for den mitokondrielle permeabilitetsovergangspore i indstillingen af coenzym Q-overskud
JoVE Journal
Biology
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JoVE Journal Biology
Assessment of Open Probability of the Mitochondrial Permeability Transition Pore in the Setting of Coenzyme Q Excess
DOI:

07:35 min

June 01, 2022

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Chapters

  • 00:04Introduction
  • 00:37Mitochondrial Oxygen Consumption and Membrane Potential (ΔΨ)
  • 05:25Results: Determination of Voltage Threshold for mPTP Opening in Neonatal Fragile X Syndrome Mice
  • 07:03Conclusion

Summary

Automatic Translation

Denne metode udnytter bidraget fra den mitokondrielle permeabilitetsovergangspore til protonlækage med lav konduktans for at bestemme spændingstærsklen for poreåbning hos neonatale skrøbelige X-syndrommus med øget kardiomyocytmitokondrie-coenzym Q-indhold sammenlignet med vildtypekontrol.

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